Phytochemical For Piper Longum
Piper Longum Extract
Herbal Extracts
 
 Piper Longum

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Botanical Name: Piper Longum
English/Common Name:
Long piper
Ayurvedic Name:
Krishna Pipali
Parts used:
Fruits
Principal Constituents: Piperine

Introduction: 
It is having slender, aromatic, perennial climber, with woody roots and numerous wide ovate, cordate leaves.  The inflorescence is a cylindrical, pedunculate spike, the  female flower is up to 2.5 cm long and 4-5 mm in  diameter but the male flower is larger and slender. The  fruits are small, ovoid berries, shiny blackish green,  embedded in fleshy spikesA slender aromatic, perennial climber, native of the indo-Malayan region, is found growing wild in the tropical rainforest of India, Nepal, Indonesia, Sri Lanka, Timor and Philippines. India long pepper is mostly derived from wild plants but is also grown in small area in the Khasi hills, the lower hills of West Bengal, Eastern Uttar Pradesh, Madhya Pradesh, Maharastra, Kerala, Karnataka and Tamil Nadu.  


Herbal Extracts For Piper Longum

Herbal Extract for Piper Longum
Piper Longum

Chemical composition / key active constituents:
Long pepper of commerce is obtained from the unripe spikes of the plant which contain the alkaloids piperence (4-5%) and piplatin and two new al one of which is designated as alkaloids-piperolactum B and piporadione are extracted. The roots contain the alkaloids piperlonguminine (0.2-0.25%) and piperlonguimine (0.02%) besides piperine.

       Long piper Extract Manufacturer
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Chemical composition / key active constituents
Mature seeds contain typically 3.1-6.1% Levodopa, although up to 12.5% has been recorded. The leaves tend to contain around 0.5%.When looking at studies that take random marketed supplements off the market and analyze them, values tend to fluctuate in the lower range of 3.8-4.3%.

Tryptamine compounds (hallucinogenic compounds) are at rather low dosages in the leaves and non-existent in the seeds; 0.006% Dimethyltryptamine, 0.0025% 5-MeO-Dimethyltryptamine, and 0.003% Dimethyltryptamine Oxide. 5-MeO-Dimethyltryptamine (Bufotenin) has been noted to be as high as 4.14ug/g in the root, but was not present in the pod.

Pharmacology:
Long pepper contains the alkaloid piperine (about 6%), which is slightly higher than in black pepper. Piperine has diverse pharmacological activities including nerve depressant and antagonistic effect on electro-shock and chemo-shock seizures, as well as muscular incoordination. It also contains one per cent essential oil, which exhibits antibacterial activities. A common use of the fruit is in the prevention of recurrent attacks of bronchial asthma (charakasamhita) and in malaria. The extract from the fruit of piper longum is standardized to a minimum of 1% alkaloid piperine. In a few weeks-clinical study with 20 children Piper longum extract significantly benefited respiratory function. Piper longum also enhances thermogenic response. 

Usage:

  • Headache
  • Toothache
  • Asthma
  • Bronchitis
  • Cholera
  • Coma
  • Cough
  • Diarrhea
  • Epilepsy
  • Fever
  • Stomachache
  • Stroke
  • Indigestion
  • Menstrual disorders
  • Other conditions
More evidence is needed to rate the effectiveness of Indian long pepper for these uses.

Dosage:
Powder- 500 mg to 1 gms.

 
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DISCLAIMER:
Patented products protected by valid patents are not offered for sale in countries where the sale of such products constitutes patent infringement and the liability for patent infringement is exclusive at buyer's risks.

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

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