Phytochemical For Mucuna Prurience
Natural Mucuna Prurience Extract
Herbal Extracts
 Mucuna Prurience

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Botanical Name: Mucuna pruriens
English/Common Name:
Horse- eye bean, Common Cowitch, Kaucha
Ayurvedic Name:
Atmagupta, Kapikacchhu
Parts used:
Roots, Leaves, seeds, hairs.
Principal Constituents: Levodopa

The plant is an annual, climbing shrub with long vines that can reach over 15 m in length. When the plant is young, it is almost completely covered with fuzzy hairs, but when older, it is almost completely free of hairs. The leaves are tripinnate, ovate, reverse ovate, rhombus-shaped or widely ovate. The sides of the leaves are often heavily grooved and the tips are pointy.In young M.pruriens plants, both sides of the leaves have hairs. The stems of the leaflets are two to three millimeters long. Additional adjacent leaves are present and are about 5 mm long.

The flower heads take the form of axially arrayed panicles. They are 15 to 32 cm long and have two or three, or many flowers. The accompanying leaves are about 12.5 mm long; the flower stand axes are from 2.5 to 5 mm. The bell is 7.5 to 9 mm long and silky. The sepals are longer or of the same length as the shuttles. The crown is purplish or white.
Phytochemcials For Mucuna pruriens

Mucuna Prurience Extract Supplier
Mucuna Prurience

The flag is 1.5 mm long. The wings are 2.5 to 3.8 cm long. In the fruit ripening stage, a 4 to 13 cm-long, 1 to 2 cm-wide, unwinged, leguminous fruit develops. There is a ridge along the length of the fruit. The husk is very hairy and carries up to seven seeds. The seeds are flattened uniform ellipsoids, 1 to 1.9 cm long, 0.8 to 1.3 cm wide and 4 to 6.5 cm thick. The hilum, the base of the funiculus (connection between placenta and plant seeds) is a surrounded by a significant arillus (fleshy seed shell).

M.pruriens bears white, lavender, or purple flowers. Its seed pods are about 10 cm lonG and are covered in loose, orange hairs that cause a severe itch if they come in contact with skin. The chemical compounds responsible for the itch are a protein, mucunain and serotonin.[3] The seeds are shiny black or brown drift seeds.The dry weight of the seeds is 55 to 85 g/100 seed.

Mucuna Prurience Extract
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Chemical composition / key active constituents
Mature seeds contain typically 3.1-6.1% Levodopa, although up to 12.5% has been recorded. The leaves tend to contain around 0.5%.When looking at studies that take random marketed supplements off the market and analyze them, values tend to fluctuate in the lower range of 3.8-4.3%.

Tryptamine compounds (hallucinogenic compounds) are at rather low dosages in the leaves and non-existent in the seeds; 0.006% Dimethyltryptamine, 0.0025% 5-MeO-Dimethyltryptamine, and 0.003% Dimethyltryptamine Oxide. 5-MeO-Dimethyltryptamine (Bufotenin) has been noted to be as high as 4.14ug/g in the root, but was not present in the pod.

In addition to levodopa, it contains minor amounts of serotonin (5-HT), 5-HTP, nicotine, N,N-DMT (DMT), bufotenine, and 5-MeO-DMT. As such, it could potentially have psychedelic effects, and it has purportedly been used in ayahuasca preparations.

The mature seeds of the plant contain about 3.1–6.1% L-DOPA, with trace amounts of 5-hydroxytryptamine (serotonin), nicotine, DMT-n-oxide, bufotenine, 5-MeO-DMT-n-oxide, and beta-carboline. One study using 36 samples of the seeds found no tryptamines present in them.

The leaves contain about 0.5% L-DOPA, 0.006% dimethyltryptamine (DMT), 0.0025% 5-MeO-DMT and 0.003% DMT n-oxide.

The ethanolic extract of leaves of Mucuna pruriens possesses anticataleptic and antiepileptic effect in albino rats. Dopamine and serotonin may have a role in such activity.


  • Parkinson's disease. Developing research suggests that some cowhage preparations might help improve symptoms of Parkinson's disease when used in combination with prescription drugs such as amantadine, selegiline, and anticholinergic agents. Cowhage contains levodopa (L-dopa), a chemical used to treat Parkinson’s disease.
  • High levels of a hormone called prolactin (hyperprolactinemia). There is some evidence that cowhage might be useful for treating hyperprolactinemia in men caused by the medication chlorpromazine. But cowhage does not appear to be effective for hyperprolactinemia of unknown cause in women.
  • Worm infestations
  • Bone and joint conditions
  • Muscle pain
  • Stimulating surface blood flow in conditions that involve paralysis
  • Other conditions
  • More evidence is needed to rate the effectiveness of cowhage.

Powder- 1 to 5 gm  decotion of root- 50 to 100 ml.

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These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.


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